A lung drug passed its main test and missed two others
NICE's appraisal of nintedanib shows how a trial proves a drug works: one pre-set outcome, a null hypothesis, and a p-value that either clears the bar or not.
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NICE's appraisal of nintedanib shows how a trial proves a drug works: one pre-set outcome, a null hypothesis, and a p-value that either clears the bar or not.

India dropped 13 places in the 2026 Climate Change Performance Index, from 10th to 23rd, as its emissions rose and it set no date to phase out coal.

Georges-Louis Leclerc, Comte de Buffon, worked out in 1777 that a needle tossed onto lined paper could estimate pi through chance alone.

A cost of living figure prices a fixed basket, and whose basket it is decides the answer. UK private renters saw 3.0% inflation to June 2026, retirees 2.5%.

Bhutan's 2022 happiness survey scored the nation 0.781 out of 1. Youth unemployment reached 28.6% that year, and young workers are leaving for Australia.

A census counts every resident against one fixed date, then a separate survey checks how many the count still missed, and where.

At a 1906 Plymouth livestock show, 787 people guessed an ox's weight. Most were wrong, yet their average landed within one per cent of the truth.